Turn Instant Pot on to sauté setting. Add beef and onion. Brown until beef is fully cooked. Drain off excess grease. Stir a pinch of kosher salt and pepper.  Turn off sauté setting.

Pour in the V-8 and scrape bottom of pot so that nothing is sticking. Add in the Italian seasoning, garlic, celery, potatoes, celery, and frozen vegetables.

Cover Instant Pot and secure the lid. Make sure valve is set to sealing. Set to cook on high pressure for 5 minutes. When time is up let pot sit for 10 minutes then manually vent to remove any more remaining pressure. Remove the lid.

Stir. Ladle into bowls and serve.